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promisiunea de maine sandra brown pdf download - Teresa. Sandra Brown (born January 17, 1954) is a bestselling American author of suspense novels. Born in Texas, she grew up in Maryland, and moved to.This invention is related to the drying of particulate substances, and particularly to the drying of human whole blood for transfusion. There are many problems in the handling and preservation of whole blood, both before and after the transfusion thereof. Prior to transfusion, whole blood must be collected and handled to prevent its contamination with other materials. Such contamination is undesirable because the transfused blood, which is essentially pure, must then be mixed with an infusion solution for infusion into the patient, which solution may itself contain contaminants. One particular problem with whole blood is the proper preservation thereof, especially storage thereof for long periods of time. As compared with liquid blood, the fluidity of the whole blood is very low, and the tendency of whole blood to clot is very great. Thus, there are problems of volume and of maintaining the desired characteristics of the fluid. In the storage of whole blood, it is customary to transfuse the blood into an infusion solution which is usually a dextrose-based aqueous solution. The whole blood transfusion may take place immediately after its collection, or the blood may be stored for extended periods of time before transfusion. Since the blood is not permitted to clot in its original state, it is desired that a preservative be included in the transfusion solution. Hemoglobin, a major component of blood, is also soluble in water, and therefore if a whole blood unit is stored in a dextrose-based solution, the hemoglobin can leach out of the blood cells into the transfusion solution. This is undesirable. When whole blood is stored for transfusion, it is usually desirable to limit the storage time, if possible, to a maximum of about forty-eight hours. A number of techniques have been used to limit this storage period to forty-eight hours. In general, the technique has been to chill the blood, and usually to freeze it. It is desirable to avoid freezing whole blood, because of the difficulty in achieving a uniform freezing of the whole blood, and because of the difficulty in thawing the frozen blood uniformly and completely. Furthermore, some of the disadvantages of freezing are attributable to the freezing step itself. The freezing process tends to destroy the cells of the blood, and to interfere with the properties of the cells.
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